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Biomedical Sciences

Publications by the staff
  1. Suresh Kannan Zeina Nicola, Rupert Overall, Muhammed Ichwan, Gerardo Ramirez-Rodriguez, Anna Grzyb, Giannino Patone, Kathrin Saar, Norbert Hübner, Gerd Kempermann, Systems genetics analysis of a recombinant inbred mouse cell culture panel reveals Wnt pathway member Lrp6 as a regulator of adult hippocampal precursor cell proliferation, Stem Cells. 2016;34:674–684. 
  2.  Gnanasambandan Ramanathan, Ramprasad Elumalai, Soundararajan Periyasamy and Bhaskar V. K. S. Lakkakula “Renin gene rs1464816 polymorphism contributes to chronic kidney disease progression in ADPKD” Journal of Biomedical Science, DOI 10.1186/s12929-015-0217-0 (2016) 23:1 
  3. Annapareddy SNR, Elumalai R, Lakkakula BVKS, Ramanathan G, Periyasamy S. Endothelin 1 gene is not a major modifier of chronic kidney disease advancement among the autosomal dominant polycystic kidney disease patients. J Nephropharmacol. 2016; 5(1):13-18. DOI: 10.12860/npj.2016.06. 
  4. Shiva Nagendra Reddy Annapareddy,Vinuutna Sravani Kumbakonam, Ramprasad Elumalai, Gnanasambandan Ramanathan, Soundararajan Periyasamy, Bhaskar V.K.S. Lakkakula "ECE1 gene variant shows tendency toward chronic kidney disease advancement among autosomal polycystic kidney disease patients" Hong Kong Journal of Nephrology (2016) 18, 20e25. 
  5. Ramanathan G, Sethumadavan P, Elumalai R, Durairaj Paul SF. Role of CYP2E1 (PstI/RsaI) gene polymorphisms on the tacrolimus drug toxicity of kidney transplantations among South Indians. Immunopathol Persa. 2016;2(2):e20. 
  6. JH Yusuf, D Kaliyaperumal, M Jayaraman, G Ramanathan and P Devaraju “Genetic selection pressure in TLR9 gene may enforce risk for SLE in Indian Tamils” Lupus (2016) 1–4 DOI:10.1177/0961203316659151. 
  7. Gnanasambandan Ramanathan, Santu Ghosh, Ramprasad Elumalai, Soundararajan Periyasamy & Bhaskar V.K.S. Lakkakula “Influence of angiotensin converting enzyme (ACE) gene rs4362 polymorphism on the progression of kidney failure in patients with autosomal dominant polycystic kidney disease (ADPKD)” Indian J Med Res 143, June 2016, pp 748-755 DOI:10.4103/0971-5916.191992. 
  8. Bhavna J, Kalaivani MK, Sumathy.A*, Cytotoxic and Pro-apoptotic activities of leaf extract of Croton bonplandianus Baill against Lung Cancer Cell line A549”, Indian Journal of Experimental Biology, 2016, 54, 379-385. 
  9. HV Almeida, Rajalakshmanan Eswaramoorthy, GM Cunniffe, CT Buckley, FJ O’Brien, DJ Kelly, Fibrin hydrogels functionalized with cartilage extracellular matrix and incorporating freshly isolated stromal cells as an injectable for cartilage regeneration, Acta Biomaterialia, 2016. 36, 55-62. (IF.6.022). 
  10. Yao‐Hsien Wang, Rajalakshmanan Eswaramoorthy, Chih‐Kuang Wang, Chung‐Hwan Chen, Yin‐Chi Fu, Tzu‐Lin Tsai, Je‐Ken Chang, Mei‐Ling Ho, PLGA‐linked alendronate enhances bone repair in diaphysis defect model, J Tissue Eng Regen Med, 2016, Accepted in press. (IF. 4.2). 
  11. Lu Luo, Johnnie Y.J. Chu, Rajalakshmanan Eswaramoorthy, Kevin J. Mulhall, and Daniel J. Kelly, Engineering Tissues That Mimic the Zonal Nature of Articular Cartilage Using Decellularized Cartilage Explants Seeded with Adult Stem Cells, ACS Biomater. Sci. Eng., 2016 Accepted, DOI: 10.1021/acsbiomaterials.6b00020. 
  12. Kalaivani MK, Sumathy.A*, Soundararajan, Hannah Rachel Vasanthi, In-vitro nephroprotective role of ethanolic root extract of Boerhaaviadiffusaagainst cisplatin-induced nephrotoxicity International Journal of Phytomedicine, 2016, 7, 388-395 
  13. S. Vijayalatha, PremaGurumurthy, A.Sumathy and T N. Gayatri, Structural characterization and antimicrobial activity of compounds isolated from acetone extract of piper longum fruits, The Ecoscan, 2016, 10(1&2), 25-28. 
  14.  Luo, L., Rajalakshmanan Eswaramoorthy, Mulhall, K.J., Kelly, D.J., Decellularization of porcine articular cartilage explants and their subsequent repopulation with human chondroprogenitor cells, Journal of the Mechanical Behavior of Biomedical Materials, 2015, 55, 21-31. (IF. 3.15). 
  15. Venkatachalam Deepa Parvathi, Kalyanaraman Rajagopal, Jalpan Pandya, Betty Lincoln, Ravindran Sumitha, Synthesis, characterisation and in vitro toxicity assessment of nano iron. Int. J. Nanoparticles, Vol. 8, Nos. 3/4, 2015. 
  16. Ramanathan Gnanasambandan, Elumalai Ramprasad, Periyasamy Soundararajan, Lakkakula V K S Bhaskar “Angiotensinogen gene polymorphisms and progression of chronic kidney disease in ADPKD patients” Clin Exp Nephrol DOI 10.1007/s10157-015-1183-2.
  17.  Paschos NK, Brown WE, Rajalakshmanan Eswaramoorthy, Hu JC, Athanasiou KA, “Advanced in tissue engineering through stem cell-based co-culture”. J Tissue Eng Regen Med, 2015, 9 (5), 488-503. (IF. 4.2). 
  18. L Luo, J Chu, Rajalakshmanan Eswaramoorthy, D Kelly, Engineering Tissues with Zonal Characteristics Mimicking Native Articular Cartilage using Decellularized Cartilage Grafts Seeded with Infrapatellar Fat Pad Derived Stem Cells, Tissue Engineering Part A 2015, 21, S329-S329. 
  19. Kaviarasan K, Jithu Mohanlal M, Mohammad Arif Mulla, Tarun Sharma, Das UN, Angayarkanni N. Low blood and vitreal BDNF, LXA4 and altered Th1/Th2 cytokine balance as potential risk factors for Diabetic Retinopathy. Metabolism 2015: 64(9); 958-66. 
  20. Sumitha R, Swarna Raman, Priyanka V and Deepa parvathi V In vivo and invitro genotoxicity analysis of silver nitrate. Drosophila information services. 2014; Vol 96: 40-46. 
  21. Vaidyanathan, Lalitha; Thanikachalam, Devi; Sivaswamy, Lokeswari T. S, Evaluation of wound healing potency of Cassia auriculata flower extracts using chick embryo wound model, International Journal of Pharmaceutical Sciences Review and Research; 2014, 27(2): 222-227. 
  22. MZ Fahira Reshman, R Sumitha, and V Deepa Parvathi, Genotoxic Effect of Lead Acetate on Drosophila melanogaster. Research Journal of Pharmaceutical, Biological and Chemical Sciences. 2014, Vol 0975-8585. 
  23. Betty Lincoln, Akhil Menon, V Deepa Parvathi, Sumitha Ravindran, In vivo evaluation of genotoxicty of Acoruscalamus mediated silver Nanoparticles. International Journal of Pharmaceutical Research and Bio-science; Volume 3(2): 126-132, 2014. (IF: 1.862). 
  24. H V Almeida, Rajalakshmanan Eswaramoorthy, T Vinardell, G Cunniffe, C O'reilly, F O'brien, D Kelly Combining human infrapatellar fat pad stem cells with a growth factor releasing ECM-derived scaffold to develop a single-stage therapy for cartilage repair: in vitro and in vivo assessment Journal of Tissue Engineering and Regenerative Medicine 2014, 8, 134-134. 
  25. Hajarah Hussain, Vinu Ramachandran, Samathmika Ravi, Teena Sajan, Kiruthiha Ehambaram, Venkatesh Babu Gurramkonda, Gnanasambandan Ramanathan, Lakkakula Venkata Kameswara Subrahmanya Bhaskar. “TCF7L2 rs7903146 polymorphism and diabetic nephropathy association is not independent of type 2 diabetes — a study in a south Indian population and meta-analysis” Endokrynologia Polska 2014; 65 (4) 
  26. Elumalai R, Periasamy S, Ramanathan G, Lakkakula BV. Role of endothelial nitric oxide synthase VNTR (intron 4 a/b) polymorphism on the progression of renal disease in autosomal dominant polycystic kidney disease. J Renal Inj Prev 2014; 3(3): 69-73. DOI: 10.12861/jrip.2014.21 
  27. Gnanasambandan Ramanathan, Ramprasad Elumalai, Soundararajan Periyasamy, Bhaskar VKS Lakkakula “Role of Renin-Angiotensin-Aldosterone System Gene Polymorphisms and Hypertension-induced End- stage Renal Disease in Autosomal Dominant Polycystic Kidney Disease”. Iranian Journal of Kidney Diseases | Volume 8 | Number 4 | July 2014. 
  28. Gnanasambandan Ramanathan, Sundararajan Periyasamy and Bhaskar VKS Lakkakula “NOS3 tagSNPs does not modify the chronic kidney disease progression in autosomal dominant polycystic kidney disease” Nephrology 19 (2014) 537–541. 
  29. Rajalakshmanan Eswaramoorthy, HV Almeida, SE Critchley, RE Downey, KJ Mulhall, DJ Kelly A co-culture of chondrons and infra-patellar fat pad derived stem cells isolated from osteoarthritic joints enhances chondrogenesis in both normoxic and hypoxic environments Journal of Tissue Engineering and Regenerative Medicine 2014, 8, 107-107. 
  30. Sanjay Gottipamla, Ashwin K.M., Manjunatha, Suresh Kannan, Udaykumar Kolkundkar, Raviraja N Seetharam, Isolation, expansion and characterization of bone marrow mesenchymal stromal cells in serum free conditions. Cell and Tissue Research, 2014, Apr;356(1):123-35. 
  31. Priyanka S, Parvathy V, Suresh Kannan et al., Are serum-free and xeno-free culture conditions ideal for large scale clinical grade expansion of Wharton's jelly derived mesenchymal stem cells? A comparative study. Stem Cell Research & Therapy 2014, 5:88 doi:10.1186/scrt477. 
  32. Betty Lincoln, Akhil Menon, V Deepa Parvathi, Sumitha Ravindran, In vivo evaluation of genotoxicty of Acoruscalamus mediated silver Nanoparticles. International Journal of Pharmaceutical Research and Bio-science; Volume 3(2): 126-132, 2014. (IF: 1.862) 
  33. Deepa Parvathi V, Sumitha R, and Swarna Raman, Evaluation of Genotoxicity of Ethyl Methanesulfonate (EMS) Using Human Lymphocytes. Research Journal of Pharmaceutical, Biological and Chemical. 2013; Vol 4 Issue 3 707-714. 
  34. Panchanathan E, Ramanathan G, Lakkakula BV. Effect of flupirtine on the growth and viability of U373 malignant glioma cells. Cancer Biol Med 2013; 10:142-147. doi: 10.7497/j.issn.2095-3941.2013.03.004. 
  35. Athanasiou KA, Rajalakshmanan Eswaramoorthy, Hadidi P, Hu JC, “Self-organization and the self-assembling process in tissue engineering”. Annual review of biomedical engineering, 2013,15, 115-36. (IF. 16.2) 
  36. Wu SC, Chen CH, Chang JK, Fu YC, Wang CK, Eswaramoorthy R, Lin YS, Wang YH, Lin SY, Wang GJ, Ho ML “Hyaluronan initiates chondrogenesis mainly via CD44 in human adipose-derived stem cells”. J ApplPhysiol (1985). 2013, 114, 1610-8. (IF.3.75) 
  37. Chen CH, Lin YS, Fu YC, Wang CK, Wu SC, Wang GJ, Rajalakshmanan Eswaramoorthy, Wang YH, Wang CZ, Wang YH, Lin SY, Chang JK, Ho ML, “Electromagnetic fields enhance chondrogenesis of human adipose derived stem cells in chondrogenic microenvironment in vitro”. J ApplPhysiol (1985). 2013, 114, 647-55. (IF 3.75). 
  38. G.Keerthana, M.K. Kalaivani, A.Sumathy*. In-Vitro Alpha Amylase inhibitory and Anti-oxidant activities of Ethanolic leaf extract of Croton bonplandianum, Asian Journal of Pharmacy and Clinical Research, 2013, 6 (4), 32-36. 
  39. Schultheiss, Abe,Suresh Kannan et al CXCR4 prevents dispersion of granule neuron precursors in the adult dentate gyrus. Hippocampus, 2013 Dec;23(12):1345-58.
  40. Umashankar V, Sathya Baarathi R, Kaviarasan K, Jithu M, Undurti N Das, Angayarkanni N. Molecular docking studies infer potential binding of lipoxin A4 and eicosapentaenoic acid to brain-derived neurotrophic factor. Lipids Health Dis. 2012 Sep 4;11(1):109.